氢气医学临床文献汇总20210405
氢气医学至今已经14年，研究论文早就超过1000篇，其中论著也差不多1000篇。作为一种可应用的医学气体，最重要的一个指标就是人体试验的论文，人体试验从证据层次上高于动物实验和细胞学研究，另外人体研究的难度和制约因素比较大，因此这些研究非常宝贵。
10多年的时间已经有100多篇人体试验论文，这是非常可贵的，但是相对来说，研究论文数量仍然不够多，更大的问题是这些研究的质量仍然不够高，大多数都是个案报道和系列观察，严格的双盲安慰剂对照论文数量比较少。这正是氢气医学领域学者努力的方向。
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41. Igarashi T, Ohsawa I, Kobayashi M, Igarashi T, Suzuki H, Iketani M, Takahashi H. Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery. Sci Rep. 2016 Aug 8;6:31190.
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63. Tanaka Y, Saihara Y, Izumotani K, Nakamura H. Daily ingestion of alkaline electrolyzed water containing hydrogen influences human health, including gastrointestinal symptoms. Med Gas Res. 2019 Jan 9;8(4):160-166.
64. Hirayama M, Ito M, Minato T, Yoritaka A, LeBaron TW, Ohno K. Inhalation of hydrogen gas elevates urinary 8-hydroxy-2'-deoxyguanine in Parkinson's disease. Med Gas Res. 2019 Jan 9;8(4):144-149.
65. LeBaron TW, Larson AJ, Ohta S, Mikami T, Barlow J, Bulloch J, DeBeliso M. Acute Supplementation with Molecular Hydrogen Benefits Submaximal Exercise Indices. Randomized, Double-Blinded, Placebo-Controlled Crossover Pilot Study. J Lifestyle Med. 2019 Jan;9(1):36-43.
66. Chen JB, Pan ZB, Du DM, Qian W, Ma YY, Mu F, Xu KC. Hydrogen gas therapy induced shrinkage of metastatic gallbladder cancer: A case report. World J Clin Cases. 2019 Aug 6;7(15):2065-2074.
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68. Chen J, Mu F, Lu T, Ma Y, Du D, Xu K. A Gallbladder Carcinoma Patient With Pseudo-Progressive Remission After Hydrogen Inhalation. Onco Targets Ther. 2019 Oct 18;12:8645-8651.
69. LeBaron TW, Singh RB, Fatima G, Kartikey K, Sharma JP, Ostojic SM, Gvozdjakova A, Kura B, Noda M, Mojto V, Niaz MA, Slezak J. The Effects of 24-Week, High-Concentration Hydrogen-Rich Water on Body Composition, Blood Lipid Profiles and Inflammation Biomarkers in Men and Women with Metabolic Syndrome: A Randomized Controlled Trial. Diabetes Metab Syndr Obes. 2020 Mar 24;13:889-896.
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77. Yang F, Yue R, Luo X, Liu R, Huang X. Hydrogen: A Potential New Adjuvant Therapy for COVID-19 Patients. Front Pharmacol. 2020 Oct 15;11:543718.
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80. Guan WJ, et al. Hydrogen/oxygen mixed gas inhalation improves disease severity and dyspnea in patients with Coronavirus disease 2019 in a recent multicenter, open-label clinical trial. J Thorac Dis 2020;12(6):3448-3452.
81. Alharbi AAD, Ebine N, Nakae S, Hojo T, Fukuoka Y. Application of Molecular Hydrogen as an Antioxidant in Responses to Ventilatory and Ergogenic Adjustments during Incremental Exercise in Humans. Nutrients. 2021 Jan 30;13(2):459.
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