主要原因是，1，论文每天都在更新，这是一个动态的数值，你即使现在搞清楚了，以后仍然有可能会不准确。2、哪些属于医学研究论文，这也是个没有标准答案的问题。有一些非常重要的观点，就是只有看法，但没有具体研究证据，算不算？有更多相关研究论文综述，算不算？3、和医学相关的生物学研究，例如对微生物，真菌，甚至植物的效应。一般不认为是医学研究，但这些研究对于理解氢气的生物医学效应，了解整个领域的研究进展，都是非常重要的。

但是总结和整理氢气医学研究论文，对于全面了解氢医学研究进展，是非常重要的工作。尤其是对下游从事氢健康产品推广的企业，全面掌握这方面的信息更为重要。作为氢健康企业，本应该在这方面投入一定资源，随时整理氢医学研究文献。根据我的观察，国内很少有企业在这方面有系统性工作。日本Miz公司是这方面非常值得让人尊敬的企业，一直在这方面非常重视，不仅有自己的文献汇编，而且经常进行更新。更重要的是，他们把整理的资料在网上公布，这大大方便了大家。Miz公司的氢医学文献目录有几个突出几个特点是，1，只收录医学相关文献，2 只收录原始文献，3，按照疾病、使用方法、研究类型等进行了分类。

我主要参考该公司的氢医学文献目录，并对文章题目的核心含义进行中文解释，以方便大家使用。对文献按照第一作者的英文字母顺序排列给大家介绍。

1.Ogawa H, Okada M, Shudou M, et al (2017): Prevention of ischemia-induced hearing loss by intravenous administration of hydrogen rich saline in gerbil. Neurosci Lett. 6; 665:195-199. 氢气生理盐水静脉注射预防沙土鼠缺血诱导听力丧失

2.Oharazawa H, Igarashi T, Yokota T, et al (2010): Protection of the retina by rapid diffusion of hydrogen: administration of hydrogen loaded eye drops in retinal ischemia-reperfusion injury. Invest Ophthalmol Vis Sci, 51: 487-492. 含氢气滴眼液保护视网膜缺血再灌注损伤

3.Ohsawa I, Ishikawa M, Takahashi K, et al (2007): Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat Med, 13: 688-694. 氢气是一种选择性抗氧化治疗物质，能选择性中和毒性氧自由基

4.Ohsawa I, Nishimaki K, Yamagata K, et al (2008): Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. Biochem Biophys Res Commun, 377: 1195-1198. 氢水预防apoE敲除小鼠动脉硬化

5.Okamoto A, Kohama K, Aoyama-ishikawa M, et al (2016): Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production. Surgery, 160: 623-631. 腹腔注射富氢生理溶液可预防术后肠梗阻，并可减少一氧化氮的产生。

6.Oláh O, Tóth-Szűki V, Temesvári P, et al (2013): Delayed neurovascular dysfunction is alleviated by hydrogen in asphyxiated newborn pigs. Neonatology. 104:79-86.氢气对窒息猪新生儿迟发性神经血管功能障碍的缓解

7.Ono H, Nishijima Y, Adachi N, et al (2011): Improved brain MRI indices in the acute brain stem infarct sites treated with hydroxyl radical scavengers, Edaravone and hydrogen, as compared to Edaravone alone. A non-controlled study. Med Gas Res, 1: 12.氢气和依达拉奉对急性脑干缺血治疗的比较研究，人体试验

8.Ono H, Nishijima Y, Adachi N, et al (2012): Hydrogen (H2) treatment for acute erythymatous skin disease. A report of 4 patients with safety data and a non-controlled feasibility study with H2 concentration measurement on two volunteers. Med Gas Res, 2: 14.氢气对急性皮肤病的非对照研究

9.Ono H, Nishijima Y, Ohta S, et al (2017): Hydrogen Gas Inhalation Treatment in Acute Cerebral Infarction: A Randomized Controlled Clinical Study on Safety and Neuroprotection. J Stroke Cerebrovasc, 26 (11): 2587-2594.氢气吸入治疗急性脑梗死，随机对照临床对安全性和神经保护的研究

10.Ono H, Nishizima Y, Sakamoto M, et al (2018): Pilot study on therapeutic inhalation of hydrogen gas for improving patients with Alzheimer’s disease assessed by cognitive subscale scores and magnetic resonance diffusion tensor imaging. Int J Alzheimers Neuro Disorder, 1: 004. 氢气改善老年性痴呆患者核磁共振成像研究

11.Ostojic SM and Stojanovic MD (2014): Hydrogen-rich water affected blood alkalinity in physically active men. Res Sports Med, 22: 49-60. 氢水改善男性体育锻炼后血液酸碱度

12.Ostojic SM, Vukomanovic B, Calleja-Gonzalez J, et al (2014): Effectiveness of oral and topical hydrogen for sports-related soft tissue injuries. Postgrad Med. 126:187-195.口服和局部氢气应用对运动相关软组织损伤的作用

13.Ozeki N, Yamawaki-Ogata A, Narita Y, et al (2019): Hydrogen water alleviates obliterative airway disease in mice. Gen Thorac Cardiovasc Surg, 68: 158-163. 氢水缓解小鼠闭塞性气道疾病。

1.Pirttila K, Videhult Pierre P, Haglof J, et al (2019): An LCMS-based untargeted metabolomics protocol for cochlear perilymph: highlighting metabolic effects of hydrogen gas on the inner ear of noise exposed guinea pigs. Metabolomics, 15 (10): 138. 氢气对噪声耳聋研究，豚鼠模型代谢组学技术

2.Pan Z, Zhao Y, Yu H, et al (2015): Effect of hydrogen-rich saline on cardiomyocyte autophagy during myocardial ischemia-reperfusion in aged rats. Zhonghua Yi Xue Za Zhi, 95: 2022-2026. (in Chines). 氢气生理盐水对心脏细胞自噬的作用，老年大鼠心脏缺血再灌注损伤模型，中文

3.Paulis MG, Hassan OA, Abbass MF, et al (2018): Structural and lipid peroxidation effects of lead on rat hippocampus and its attenuation by hydrogen rich water. J Chem Neuroanat. 91: 55-62. 铅对大鼠海马结构和脂质过氧化的影响及富氢水对其衰减作用。

4.Peng Z, Chen W, Wang L, et al (2015): Inhalation of hydrogen gas ameliorates glyoxylate-induced calcium oxalate deposition and renal oxidative stress in mice. Int J Clin Exp Pathol, 8: 2680-2689.氢气吸入预防草酸诱导肾结石形成