Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
I Ohsawa, M Ishikawa, K Takahashi, M Watanabe… - Nature medicine, 2007 - nature.com
Acute oxidative stress induced by ischemia-reperfusion or inflammation causes serious
damage to tissues, and persistent oxidative stress is accepted as one of the causes of many
common diseases including cancer. We show here that hydrogen (H2) has potential as an
antioxidant in preventive and therapeutic applications. We induced acute oxidative stress in
cultured cells by three independent methods. H2 selectively reduced the hydroxyl radical,
the most cytotoxic of reactive oxygen species (ROS), and effectively protected cells; …
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