到底有多少篇氢医学研究论文，这不是一个容易回答的问题。

主要原因是，1，论文每天都在更新，这是一个动态的数值，你即使现在搞清楚了，以后仍然有可能会不准确。2、哪些属于医学研究论文，这也是个没有标准答案的问题。有一些非常重要的观点，就是只有看法，但没有具体研究证据，算不算？有更多相关研究论文综述，算不算？3、和医学相关的生物学研究，例如对微生物，真菌，甚至植物的效应。一般不认为是医学研究，但这些研究对于理解氢气的生物医学效应，了解整个领域的研究进展，都是非常重要的。

但是总结和整理氢气医学研究论文，对于全面了解氢医学研究进展，是非常重要的工作。尤其是对下游从事氢健康产品推广的企业，全面掌握这方面的信息更为重要。作为氢健康企业，本应该在这方面投入一定资源，随时整理氢医学研究文献。根据我的观察，国内很少有企业在这方面有系统性工作。日本Miz公司是这方面非常值得让人尊敬的企业，一直在这方面非常重视，不仅有自己的文献汇编，而且经常进行更新。更重要的是，他们把整理的资料在网上公布，这大大方便了大家。Miz公司的氢医学文献目录有几个突出几个特点是，1，只收录医学相关文献，2 只收录原始文献，3，按照疾病、使用方法、研究类型等进行了分类。

我主要参考该公司的氢医学文献目录，并对文章题目的核心含义进行中文解释，以方便大家使用。对文献按照第一作者的英文字母顺序排列给大家介绍。

1. Igarashi T, Ohsawa I, Kobayashi M, et al (2016): Hydrogen prevents corneal endothelial damage in phacoemulsification cataract surgery. Sci Rep, 6: 31190. 氢气保护白内障乳化手术晶状体内皮损伤

2. Igarashi T, Ohsawa I, Kobayashi M, et al (2019): Effects of hydrogen in prevention of corneal endothelial damage during phacoemulsification: A prospective randomized clinical trial. Am J Ophthalmol, 207: 10-17. 氢气对白内障乳化手术晶状体内皮细胞保护的临床试验

3. Ignacio RM, Yoon YS, Sajo MEJ, et al (2013a): The balneotherapy effect of hydrogen reduced water on UVB-mediated skin injury in hairless mice. Mol Cell Toxicol, 9: 15-21. 氢水洗浴对紫外线导致的皮肤损伤保护作用，无毛小鼠

4. Ignacio RM, Kwak HS, Yun YU, et al (2013b): The drinking effect of hydrogen water on atopic dermatitis induced by Dermatophagoides farina allergen in NC/Nga mice. Evid Based Complement Alternat Med, 2013, Article ID 538673, 氢水饮用对特异性皮炎，尘螨过敏小鼠

5. Iio A, Ito M, Itoh T, et al (2013): Molecular hydrogen attenuates fatty acid uptake and lipid accumulation through downregulating CD36 expression in HepG2 cells. Med Gas Res, 3: 6氢气通过下调CD36表达降低 HepG2细胞的脂肪酸摄取和脂类聚集

6. Ikeda M, Shimizu K, Ogura H, et al (2017): Hydrogen-rich saline regulates intestinal barrier dysfunction, dysbiosis and bacterial translocation in a murine model of sepsis. Shock, 2017 Dec 29. 氢气盐水调节脓毒症动物肠道屏障，菌群移位 

7. Iketani M, Ohshiro J, Urushibara T, et al (2016): Preadministration of hydrogen-rich water protect against lipopolysaccharide-induced sepsis and attenuates liver injury. Shock, 2016 Dec 1. 氢水保护内毒素诱导脓毒症和肝损伤

8. Iketani M, Sekimoto K, Igarashi T, et al (2018): Administration of hydrogen-rich water prevents vascular aging of the aorta in LDL receptor-deficient mice. Sci Rep, 8: 16822. 氢水对LDL受体缺陷小鼠动脉老化的预防作用。氢气预防脂蛋白相关衰老

9. Imai K, Kotani T, Tsuda H, et al (2016): Neuroprotective potential of molecular hydrogen against perinatal brain injury via suppression of activated microglia. Free Radic Bio Med, 91: 154-163. 氢水抑制小胶质细胞激活保护胎儿脑损伤

10. Ishibashi T, Sato B, Rikitake M, et al (2012): Consumption of water containing a high concentration of molecular hydrogen reduces oxidative stress and disease activity in patients with rheumatoid arthritis: an open-label pilot study. Med Gas Res, 2012, 2: 27. 氢水降低类风湿关节炎患者氧化应激和疾病表现，开放标签临床研究

11. Ishibashi T, Sato B, Shibata S, et al (2014): Therapeutic efficacy of infused molecular hydrogen in saline on rheumatoid arthritis: A randomized, double-blind placebo-controlled pilot study. Int Immunopharmacol, 21: 468-473. 氢气盐水注射治疗类风湿关节炎的RCT临床研究

12. Ishibashi T, Ichikawa M, Sato B, et al (2015): Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases. Mol Med Rep, 2015 Apr 30. doi: 10.3892/mmr.2015.3707. 用氢水治疗对银屑病相关关节炎和皮肤损害的改善

13. Ishibashi T, Kawamoto K, Komori N, et al (2020): Molecular hydrogen suppresses superoxide generation in the mitochondrial complex I and reduces mitochondrial membrane potential. Biochem Biophys Res Commun, 522: 965-970. 氢气减少线粒体复合物I释放超氧阴离子自由基，降低线粒体膜电位

14. Ishibashi T, Kawamoto K, Matsuno K, et al (2020): Peripheral endothelial function can be improved by daily consumption of water containing over 7 ppm of dissolved hydrogen: A randomized controlled trial. PLoS ONE, 15: e0233484. 高浓度氢水日常饮用提高外周血管内皮细胞功能

15. Itoh T, Fujita Y, Itoh M, et al (2009): Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun, 389: 651-656. 氢气治疗哮喘的细胞信号效应研究

16. Itoh T, Hamada N, Terazawa R, et al (2011): Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. Biochem Biophys Res Commun. 411: 143-149.氢气抑制内毒素诱导巨噬细胞信号传导和NO合成

17. Ito H, Kabayama S, Goto K (2020): Effects of electrolyzed hydrogen water ingestion during endurance exercise in a heated environment on body fluid balance and exercise performance. Temperature (Austin), 7: 290-299. 热环境耐力训练时电解水对运动员体液平衡和运动表现的影响

18. Ito M, Ibi T, Sahashi K, et al (2011): Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen enriched water for mitochondrial and inflammatory myopathies. Med Gas Res, 1: 24. 氢水对线粒体肌肉病和炎症性肌肉病的临床试验

19. Ito M, Hirayama M, Yamai K, et al (2012): Drinking hydrogen water and intermittent hydrogen gas exposure, but not lactulose or continuous hydrogen gas exposure, prevent 6-hydorxydopamine-induced Parkison’s disease in rats. Med gas Res, 2: 15. 氢水和间歇性氢气吸入、和乳果糖或持续氢气吸入对帕金森病治疗效果的比较。

20. Iuchi K, Nishimaki K, Kamimura N, et al (2019): Molecular hydrogen suppresses free radical-induced cell death by mitigating fatty acid peroxidation and mitochondrial dysfunction. Can J Physiol Pharmacol, 2019 Jul 11. doi: 10. 1139/cipp-2018-0741. 氢气抑制自由基诱导细胞死亡，通过降低脂肪酸过氧化和线粒体功能紊乱